Liposome
Liposome — A spherical vesicle composed of a lipid bilayer used to encapsulate and deliver peptides, improving stability and cellular uptake.
What Is a Liposome?
A liposome is a spherical vesicle composed of one or more phospholipid bilayers enclosing an aqueous core. In peptide delivery, liposomes encapsulate hydrophilic peptides in the aqueous interior or embed hydrophobic peptides in the lipid bilayer, protecting them from enzymatic degradation and controlling release kinetics.
Advantages for Peptide Delivery
- Protection: Lipid bilayer shields encapsulated peptides from plasma proteases
- Controlled release: Peptide diffuses through or is released upon bilayer degradation
- Targeting: Surface-decorated with targeting peptides or antibodies for site-specific delivery
- Biocompatibility: Phospholipid composition mimics natural cell membranes
Frequently Asked Questions
What is Liposome?
A spherical vesicle composed of a lipid bilayer used to encapsulate and deliver peptides, improving stability and cellular uptake.
Why is Liposome important in peptide research?
Liposome is a fundamental concept in technology as it relates to peptide science. It directly influences experimental design, compound characterization, and the reliability of research outcomes across biochemistry and molecular biology disciplines.