Lactoferricin
Lactoferricin — An antimicrobial peptide derived from the N-terminal region of lactoferrin, studied for broad-spectrum activity against bacteria and fungi.
What Is Lactoferricin?
Lactoferricin is a 25-amino acid cationic antimicrobial peptide released by pepsin digestion of bovine lactoferrin. Lactoferricin B (LfcinB, residues 17-41 of lactoferrin) has broad-spectrum antibacterial, antifungal, antiviral, and anti-cancer activities. Its mechanism involves direct membrane disruption of microbial and tumor cells.
Research
- Structure: Amphipathic loop stabilized by single disulfide bond (Cys19-Cys36)
- Anti-cancer: Selectively kills cancer cells at concentrations non-toxic to normal cells
- Food safety: Natural nutraceutical antimicrobial from milk protein digestion
Frequently Asked Questions
What is Lactoferricin?
An antimicrobial peptide derived from the N-terminal region of lactoferrin, studied for broad-spectrum activity against bacteria and fungi.
Why is Lactoferricin important in peptide research?
Lactoferricin is a fundamental concept in compound as it relates to peptide science. It directly influences experimental design, compound characterization, and the reliability of research outcomes across biochemistry and molecular biology disciplines.