Benzyl Alcohol
Benzyl Alcohol — An aromatic alcohol used at 0.9% concentration as a bacteriostatic preservative in sterile water for peptide reconstitution.
What Is Benzyl Alcohol?
Benzyl alcohol is a preservative used at 0.9% (9 mg/mL) in bacteriostatic water and multi-dose injectable peptide formulations. It prevents microbial growth after initial vial puncture, enabling safe multi-dose use. Benzyl alcohol has both bacteriostatic and mild local anesthetic properties.
Considerations
- Compatibility: Some peptides are destabilized by benzyl alcohol. Stability testing required
- Contraindication: Toxic to neonates ("gasping syndrome"). Use sterile water for neonatal formulations
- Alternatives: m-Cresol (used in insulin formulations), phenol, chlorobutanol
Frequently Asked Questions
What is Benzyl Alcohol?
An aromatic alcohol used at 0.9% concentration as a bacteriostatic preservative in sterile water for peptide reconstitution.
Why is Benzyl Alcohol important in peptide research?
Benzyl Alcohol is a fundamental concept in reagent as it relates to peptide science. It directly influences experimental design, compound characterization, and the reliability of research outcomes across biochemistry and molecular biology disciplines.
Authority Sources
- Benzyl Alcohol on Wikipedia
- Search Benzyl Alcohol on PubChem (NIH)
- Research articles on ScienceDirect